Three weekends ago, Murray won Queens for a fifth time, one of the grass court preludes to Wimbledon, defeating Raonic in the final.
Murray also came back from two sets to one down to beat the big Canadian in January's Australian Open semi-finals.
"I'm not trying to put him in a box. and have him be an objective observer of the match and wear two hats", said Jamie Reynolds, an ESPN vice-president overseeing coverage of the tennis tournament.
Berdych was the runner-up to Rafael Nadal in 2010, his only appearance in a Grand Slam final, after beating Federer and Novak Djokovic along the way.
Murray, who has won his last four matches against Berdych, is more familiar with this territory. "That's what makes these events special".
The 11th Grand Slam final of Andy Murray's career will be unlike any of the others in at least one way: The opponent will not be Roger Federer or Novak Djokovic. I think that's a win, as long as everybody understands what voice he's bringing into the booth. Unexplainable for me really, yeah. They had a great run together and are now having another great run. They're very hard competitions to win. Raonic is just the second Canadian after Eugenie Bouchard to make a grand slam singles final.
"But I'd love to win it again and I have an opportunity".
He added: "Milos is a very intelligent guy".
"Federer is the best grass-court player ever - probably the best player of all time on all surfaces - and Milos beat him. So he deserves to be there".
Rekindling his coaching partnership with Ivan Lendl, who guided Murray to his two previous major triumphs, has also added an extra dimension to his game.
"I think he can (win), yeah".
"But I obviously wanted to work with Ivan again to try to help me win these events. And that's the goal".
Overall Murray is 6-3 in his career against Raonic, winning each of their last five head-to-head matchups including the final of the AEGON Championship in London just last month.
Andy Murray has played in 10 Grand Slam finals but will experience something new this weekend - the pressure of being the favourite. "I believe I am, but I'll know more tomorrow when I wake up".
"I mentioned that a lot beforehand".
Murray was even asked by a reporter during Wimbledon how it felt being Britain's "last hope", a question he jokingly dismissed by replying, "It's not that bad, is it?"
"There have been bumps throughout this week".
"Not that I was anxious it was going to end somehow, but I was insecure coming into Wimbledon".
Maybe now I'm more excited than when I was younger. Lendl and Judy (Murray's mother) are very stoic, they stay flawless, do not let him in one iota. "So close", said Federer, who had his surgically repaired left knee checked by a trainer after the uncharacteristic fall and wasn't sure whether he was seriously injured.
"He's given himself a lot of opportunity through that". You start to appreciate the history of the events more.
"He'll try to throw you off, give you some slower balls, some harder balls, all these kinds of things".
"I guess my goal is to keep him away from that, play it on my terms, be aggressive, not hesitate". He says. 'There's no too calm for you. Over and over, Murray managed to get the ball back, even one that came in at 147 miles per hour.