Ever since, he had spoken of trying to deliver to Portugal that long-craved glory, and having finally reached the precipice again, he broke down once it was clear that he would not be able to see it through.
Sadness was felt all around fan zones in and around Paris following the host nation's shock defeat in the Euro 2016 final to Portugal.
After the match ended 1-0, fireworks and music broke out across the capital where the game had been shown on television screens.
Eder's strike in extra time proved to be decisive as Lloris missed a chance to lift a major global trophy on home soil.
It could be an uncomfortable few months ahead for Eder, the unheralded striker who will return shortly to French club Lille after breaking French hearts with his 109th-minute goal.
It didn't seem to be going Portugal's way in the ninth minute when Dimitri Payet's right knee clattered into Ronaldo's standing left leg.
Ronaldo was just 19 when he played in the Euro 2004 final, which Portugal lost 1-0 to Greece in Lisbon.
"If they won the tournament, it is because they deserved it", Lloris said. They didn't necessarily play positive football over the tournament, and they only won one match in 90 minutes, but it showed great strength of character for them to win this.
The 31-year-old was seen combining with coach Fernando Santos on the sidelines, encouraging and issuing tactical instructions to his teammates to inspire their nation to their first ever global trophy.
Four Portuguese players and three from Germany were named in the team of the tournament.
"We haven't slept much, this is our first victory, we had to be here", said one fan, 21-year-old student Antonio Ribeiro de Magalhaes. "I will commemorate them with the Order of Merit of Commanders - that is a decree that has never been given to the national team", he told broadcaster RTP.
Pepe returned from a thigh problem to start the European Championship final at the Stade de France.
Soares also said that Ronaldo had words of encouragement for every player, and it was his fighting attitude that helped the players to continue the battle on the pitch. I am not a wizard or a visionary but I always follow my feelings.
Cristiano Ronaldo passing on instructions to his teammates during the Euro 2016 final vs France. Suddenly, for the first time in 24 major tournament games, Portugal had to play without their superstar. We have a lot of Portuguese in France.