The Merseyside club are unbeaten against the other teams in the current top-six this season, winning five of their nine league games against City, Manchester United, Arsenal, Tottenham Hotspur and Chelsea.
Liverpool manager Jurgen Klopp does not agree with the scrutiny counterpart Pep Guardiola is coming under following Manchester City's Champions League exit but that does not mean he will be sympathetic towards the Catalan on Sunday.
"We have to defend better".
"I think there were other games we played much better than these games", he admitted in his weekly press conference.
Under-pressure City manager Pep Guardiola may have found an unexpected ally in Klopp as the Liverpool boss has nothing but praise for the Spaniard.
"They need the process, they need time to build and to be settled, but I am delighted with his performance and how good he will be for your national team in the future, I am pretty sure of that, how important he will be". You have to win all of the decisive challenges, all of them.
Rocked by the humiliation of a 10-2 aggregate defeat against Bayern Munich in the Champions League last 16, Wenger has endured calls for his resignation from angry fans and failing to finish in the top four might convince the Frenchman to step down.
"I think it's part of football that these things can happen". We (Borussia Dortmund) tried as hard as possible to be it (a rival on terms) but for different reasons it was not possible.
Klopp confirmed captain Jordan Henderson and forward Daniel Sturridge will both miss the trip to the Etihad Stadium, while Divock Origi and Roberto Firmino are doubts having missed training during the week.
"You've still got to pay their wages, let's make no bones about it, it's the money that attracts them first".
"It's the first year players have come here to play in Europe, and people believe they are going to come here, put them on the pitch and they are going to play well".
"But two spectacular games".
In 2014, the Senegalese flyer was at Red Bull Salzburg in Austria, on the back of a second consecutive season in which he'd scored 20 goals.
"I thought the changes City made in the game were really good but which mood they are now? You have to be active and to be active you need to be fearless". "We can not hope Aguero misses these chances". That is what anxious me the most.
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