Given the high purity of the gold used in the coin, its material value is estimated to be $4m (£3.18m).
The 3cm (1.18in) thick coin, with a diameter of 53cm (20.9in), has a face value of €920,000.
The coin features Queen Elizabeth II on one side and a maple leaf on the other. Thought to have a material value of as much as 4 million U.S. dollars, the coin was made in Canada and called Big Maple Leaf.
Thieves broke in to the Bode Museum in Germany's capital in the early hours of the morning and made off with the 100 kilogram "Big Maple Leaf" coin. The Berlin police has asked any one who noticed anything suspicious between 2am and 4am in the vicinity of the museum to come forward. "They then managed to enter the building and went to the coin exhibition".
A ladder was later found near railway tracks close to the museum. Weitere Fragen unseres #LKA:https://t.co/9hHf8bJwH6 pic.twitter.com/uTBZh5h5jp- Polizei Berlin (@polizeiberlin) March 27, 2017 Police spokesman Winfred Wenzel said: "The coin was secured with bullet-proof glass inside the building".
On show at the Bode Museum since 2010, it is part of the Münzkabinett collection, Berlin's most important archive of coinage, which includes more than 540,000 objects altogether.
By the time officers arrived the 221lbs coin, known as the Big Maple Leaf, was gone along with the criminals.