Spending enough money to scald a wet mule (to borrow a phrase from Haley Barbour) to hold on to a district that Tom Price (Trump's HHS secretary) and Newt Gingrich held is not a sign of Republican health.
And while experts say the demoralizing loss isn't necessarily a harbinger of more losses to come in the 2018 midterms, it has Democrats taking stock and asking whether it's time for new party leadership - specifically whether House Minority Leader Nancy Pelosi should step aside.
His online messaging comes after GOP candidate Karen Handel defeated her Democratic opponent Jon Ossoff on Tuesday in a highly watched race in Georgia that was the most expensive House contest ever. With the Georgia victory, Republicans showed that they could still win in the kind of affluent, educated districts where Democrats have made gains and Trump's populist agenda was sometimes a tough sell.
Handel, 55, fended off Jon Ossoff, a 30-year-old Democrat and political newcomer who emerged from obscurity to raise $25 million from progressives across the country eager to express their anger at Trump.
Trump tweeted that Democrats should help Republicans pass the latter's agenda on health care and taxes, saying obstruction hasn't helped them win elections.
Handel's handy victory over Democrat Jon Ossoff follows GOP special election wins in Kansas, Montana and SC. He earned 48 percent compared to former Georgia Secretary of State Karen Handel's 52 percent showing in the race.
Republicans have actually won four races, with Democrats capturing a fifth seat. "Fantastic job, we are all very proud of you!" But Georgia, they said, could well be different. None of the special elections in Georgia previous year had more than a 15 percent voter turnout rate. The South Carolina race, in a district to replace Trump's budget chief, could have used more attention.
Pollster Robert Cahaly told Politico the high turnout likely meant Handel would win because Georgia's sixth district, which includes Atlanta's northern suburbs, is generally red.
Each of the special elections so far have also come with their quirks: For instance, Georgia 6 had a very high turnout and tens of millions of dollars invested by each party, whereas SC 5 had a much lower turnout and very little investment.
Six women have served in Congress representing Georgia as Democrats since 1940, including Rep. Cynthia McKinney, who served several terms in Congress, most recently from 2005-2007, according to Rutgers University's Center for American Women and Politics.