Third-ranked Matsuyama, trying to become the first Japanese man to win a major title, and 25th-ranked American Kisner, who won his second United States tour title in May at Colonial, still shared the second-round lead on eight-under par 134.
Kisner hasn't fared well in a dozen major appearances, but that hasn't changed his attitude when it comes to vying for the biggest wins in the sport. "As I said, I still feel I'm right there in the tournament". He barely missed a birdie putt on the 18th hole that would have given him sole possession of the lead. Yet, after going to three-over a couple of times, I am very happy with the way I finished with two birdies on seventh and ninth and a very short miss on eighth in between.
Now he's back in one of the final groups Sunday at a major, ready to receive the Wanamaker Trophy or another painful lesson. "Even just that - so yeah, it's a much tougher practice, and I'm not - after what I've witnessed over the past two days, no, I'm not surprised to see so many guys be over par".
"With the way I've been playing, how I'm swinging this week and last week going into it, I know I can win this week", Fowler said.
SHOT OF THE DAY: DeLaet almost bagged a hole-in-one at the par-4 14th; his tee shot hitting the hole and bouncing out.
"I've always fought a push to the right and got sick and exhausted of it", said Kisner. "I hit a lot of fairways and never really got out of position off the tee".
Italy's Francesco Molinari and South African Louis Oosthuizen shared fifth on 137, three strokes off the pace, with England's Paul Casey and Americans Rickie Fowler and Justin Thomas sharing seventh on 139.
McGirt, who teed off at 1:10 p.m. Friday, completed 11 holes before the horn sounded while he was preparing for a putt on the par-4 third hole.
Japan's Matsuyama, the world number three, moved to eight under despite a stoppage of nearly two hours because of potentially "dangerous" weather.
The 30-year-old Kiwi climbed from 80th overnight at Quail Hollow into a share of 11th, amassing six birdies with his only blemish a bogey at the par-four 11th.
Three weeks after Spieth got the third leg of the Grand Slam by winning the British Open, his putting stroke hasn't helped him at Quail Hollow. The former British Open champion appeared to injure his wrist hitting off of a tree root on the par-4 fifth hole, but he chose to keep playing after meeting with a trainer. He finished fourth in this event last year and has placed in the top 15 in all three majors this year.
McGirt will stay in the Tar Heel state for next week's Wyndham Championship in Greensboro at Sedgefield Country Club.
Stroud won on the PGA Tour for the first time last week at the Barracuda Championship, outlasting Greg Owen and Richy Werenski in a playoff to earn the final spot in the field at Quail Hollow.