-Tyrod Taylor finished the game 9-18 for 56 yards and an interception for a passer rating of 33.6. The last time the Bills allowed a pair of 100-yard rushers was against New England in 2012. Facing a Saints team coming in on a six-game winning streak, Buffalo was quite literally run out of their own building in a 47-10 defeat.
Medical personnel rushed on the field as Lasco lay motionless, and an ambulance eventually emerged from the tunnel area of New Era Field.
At worst, it is the latest example of why the Bills, now 5-4 after their back-to-back lopsided losses, are heading the wrong direction as they try to end their 17-year playoff drought.
-A pass that went off the hands of Charles Clay deep in Buffalo territory was intercepted by Sheldon Rankins and returned to the Bills three-yard line.
Mark Ingram had three touchdowns on 131 yards rushing.
The Saints (7-2) have now won seven straight and host the Washington Redskins next week.
-New Orleans had little trouble responding with a nine-play scoring drive covering 75 yards.
Among the stand-out contributors have been cornerback Marshon Lattimore and gadget running back Alvin Kamara while an ageless Drew Brees at quarterback continues to play at an elite level as he leads the league in completion percentage with only Alex Smith and Tom Brady possessing a higher QB rating.
-Buffalo's run defense gave up a season-high 298 yards rushing and six rushing touchdowns. The Chargers are coached by Anthony Lynn, who spent most of last season as the Bills' offensive coordinator and was a candidate to become their head coach.