One of the officers died and the other is undergoing surgery. The suspect may still be barricaded in a building.
Police in Pomona, about 30 miles outside Los Angeles, received reports of a barricade situation around 9:10 p.m.
Two officers have been shot and wounded in a barricade situation in Pomona Friday night.
The Pomona officer is the 16th law enforcement officer who was shot and killed this year, according to The Officer Down Memorial Page, which tracks such deaths.
Bergner says the man had led police on a pursuit Friday night before he crashed the vehicle and fled on foot.
Police responded the 1400 block of South Palomares Street about 9 p.m. Friday to a call about a reckless driver, Los Angeles County Sheriff's Captain Christopher Bergner told reporters Saturday morning. "He then began firing through the door, striking the two officers".
One of the officers was killed.
SWAT officers and crisis negotiators have been attempting to negotiate with the suspect to no avail.
A second officer who was also shot is in stable condition Saturday.
Pomona Police Chief Mike Olivieri provided grim updates over Twitter, posting: "It is with a heavy heart that I must report that one officer did not survive". Olivieri later tweeted that a police escort will take the officer's body from the hospital to the Los Angeles County coroner's office. Detailed information on a suspect or suspects was not released.
Police remained on the scene Saturday morning.