The arrestees, both 18, were detained "in connection with racially aggravated public order offences" following reports of the social media post, according to a statement by Nottinghamshire police, who reached out to Chisango in a response to her Twitter post. Male voices can be heard chanting "sign the Brexit papers" and "blacks and whites will never live together".
In response to the tweet, Edward Peck, the vice-chancellor of Nottingham Trent University, said: "All @TrentUni are appalled at this behavior which will not be tolerated".
On Twitter she wrote: "Okay this happened Monday night, the video wasn't able to catch what else they were saying which was "blacks would go back to picking cotton".
Rufaro Chisango, the only black student on her floor, filmed the video from inside her room on Monday night, where the chanting was happening directly outside of her door.
"We are also cooperating fully with the police, who have launched a criminal investigation and have made arrests", the university said in a statement.
A Nottinghamshire Police spokesperson said: "We treat hate crime as a priority". "Our enquiries are ongoing".
"Nottingham Trent is a really diverse and it seems like such a nice, safe place".
In its statement, the university told CNN: "We are also working with our accommodation partner to understand why the University was only alerted to this on Wednesday evening after this was reported to them in the very early hours of Tuesday".
Labour MP David Lammy joined the calls for action, tweeting Rufaro: "Please contact the police and your member of parliament and cc me in".
Video of the incident spurred messages of support from fellow students, friends and even government leaders. "All my love and solidarity ... my heart breaks for this young woman and I have the utmost respect for her bravery in speaking out".
Prof Eunice Simmons, deputy vice chancellor at NTU, admitted: "There was a significant delay in dealing with this incident and that is completely unacceptable". Chisango emphasized the fact that she's the only Black student on her floor.
"But I want to highlight how serious this is".