The Court of Appeal in the United Kingdom ruled against the parents of a 23-month-old boy on life support.
Judges have heard that Alfie, born on May 9 2016, is in a "semi-vegetative state" and has a degenerative neurological condition doctors had not definitively diagnosed.
Alfie Evans' parents are headed back to court today in their desperate attempt to save his life and stop a children's hospital from yanking his life support over their objections.
Mr Evans and Ms James have previously taken the Bootle toddler's case to the High Court, Supreme Court and the European Court of Human Rights.
Like any parent of a very sick child, Alfie's parents want to be able to spend as much time with him as possible while he's in the hospital - especially with a protracted legal battle that could result in yanking his life support and ending his life at any time.
In a statement tearfully read outside the hospital on Monday, Alfie Evans' father accused the hospital of "lying to the police", "stripping [Alfie] of his dignity", "taking away the rights of him and his family to be together", and "trying to dictate what is in Alfie's best interests when we have several pieces of evidence showing Alder Hey to be acting contrary to Alfie's best interest", such as "leaving him in poor and squalid conditions.and with moldy tubes".
The hospital said that it would not help Alfie to subject him to further tests.
Appeal court officials said an appeal court judge had decided that Alfie should continue to receive treatment pending the outcome of Monday's Court of Appeal hearing.
In addition, Moylan said it is "wrong to say that the parents' own views can trump that judicial determination", according to LifeSiteNews.
Paul Diamond, Tom and Kate's lawyer, argued that the hospital had violated Alfie's rights by unlawfully detaining him.
The parents do, however, have the right to directly ask the Supreme Court for permission to appeal.
Last week, Mr Justice Hayden endorsed a detailed plan put forward by Alder Hey doctors for withdrawing life-support treatment, after considering a number of issues at a follow-up High Court hearing.
Speaking outside the hospital, Alfie's dad declared "it's not over" while crowds of supporters chanted "get him out".
Alfie's parents say their son has improved in recent weeks and had asked Mr Justice Hayden to allow a new assessment.
The court ruled that his life support won't be turned off until the Supreme Court has reached its decision. The hospital said noise from protesters outside the building on Sunday night had disturbed other young patients.
"The bad reality was that nearly the entirety of Alfie's brain has been eroded, leaving only water and cerebral spinal fluid", Moylan said, reading from Hayden's previous decision, according to The Sun.