The 51-year-old actor was one of the dozens of women who came forward in 2017 to accuse Weinstein of sexual harassment.
Hayek hopes that the #MeToo movement will offer a chance to men to re-examine their own roles, both in the film industry, and in society as a whole.
Halfway up the stairs at the Palais des Festivals at the Cannes Film Festival on Saturday stood 82 women, representing the 82 female directors who have climbed those same stairs since the first year the festival was held, 1946.
If there hadn't been so many accusers, Hayek added, "probably, people would've thought that we made that up". "I hope I can get a job after this!"
Weinstein has denied all allegations of non-consensual sex and disputed Salma's version of events. It is a well-known fact that if you are a woman of colour people believe in you less and believe what you say less.
Speaking to Variety magazine at the Women In Motion panel at Cannes Film Festival, she said: "The good is that there's so many". "Ask what women are paid, and say, 'If she's not paid the same as the men, I'm not doing it'".
While Weinstein and his team issued generic denials of many women's accusations, Hayek's and Nyong'o's allegations were among the small handful they addressed by name. The protest ended with Cate Blanchett along with veteran documentary filmmaker reading a collective statement from the group which highlighted the need for institutions to provide safer working conditions for women, and for governments to uphold equal pay laws.
The actress said of herself and Nyong'o, who accused Weinstein of sexually harassing her back in 2011: "We are the easiest to get discredited".
In the wake of the scandals that have followed Weinstein's downfall, Hayek said men in Hollywood "are terrified" and that "predators are hiding". "It is happening", she said.
According to Hayek, however, it is not just women who have suffered as a outcome of powerful men abusing their positions.
Hayek - best known for Desperado and indie hit Beatriz at Dinner - had accused mogul Harvey Weinstein of threatening to "break my kneecaps" after she spurned his advances on the set of her film Frida.
One of the other early accounts that prompted an individualized apology from Weinstein was from Lupita Nyong'o, who wrote a commentary in the New York Times detailing a pattern of predatory behavior by Weinstein.
"I can't find enough female writers and directors", Hayek said.