Israel said early Thursday that Iran's Quds Force fired 20 rockets at Israeli front-line military positions in the Golan Heights.
A leading Iranian cleric said Friday that Tel Aviv and Haifa will be destroyed if Israel behaves "foolishly", while also vowing Iran will ramp up missile development despite Western criticism.
The IDF attacked multiple Iranian targets in Syria on Thursday, in one of the largest Israeli strikes on the region in decades. On Tuesday, a Syrian report claimed that Israel struck a military base south of Damascus that Iranian forces used.
In retaliation, Israel has targeted Iranian weapons depots, logistic sites and intelligence centres in Syria.
Iranian Foreign Ministry spokesman Bahram Ghasemi, quoted in state-run IRNA, said the attacks were a breach of the national sovereignty and territorial integrity of Syria.
All eyes will be on any fresh military activity Friday after Israel carried out widespread deadly raids against what it said were Iranian targets in Syria on Thursday in response to rocket fire towards its forces that it blamed on Iran.
Israeli Prime Minister Benjamin Netanyahu reiterated the Jewish State's commitment to defend itself against the Ayatollah regime.
He noted that in contacts with the leadership of both countries, including a meeting Wednesday between Putin and Netanyahu, "we underlined the necessity of avoiding any actions that might be mutually provocative".
German Chancellor Angela Merkel and French President Emmanuel Macron called for a de-escalation between the two sides.
"It was ordered and commanded by Qassem Soleimani and it has not achieved its goal", said Lt Col Jonathan Conricus, a spokesman for the Israeli Defence Forces.
"Already this week, the IRGC has fired rockets at Israeli citizens, and Iran's proxies in Yemen have launched a ballistic missile at Riyadh", it said, referring to the Iranian Revolutionary Guard Corps. Nevertheless, the north of Israel remains on high alert and security has been increased at Israeli embassies overseas.
Israel says it has conducted dozens of operations in Syria to stop what it says are advanced arms deliveries to one of its main foes, Iran-backed Hezbollah. Iran is trying to create a new front with us.
The Golan attack was "just further demonstration that the Iranian regime can not be trusted and another good reminder that the president made the right decision to get out of the Iran deal", White House press secretary Sarah Sanders told Fox News.
Lieberman said Israel was not seeking escalation on the Syrian front.
Israel said Iran has been deploying its allied militias in the area. "We will not let them use Syria as a base to attack us from". President Donald Trump's announcement Tuesday that the USA was withdrawing from the 2015 nuclear deal with Iran has triggered uncertainty and threatened to spark more unrest in the Middle East.
Have Israel and Iran always been mortal enemies? .