The hip-hop megastar, whose real name is Aubrey Drake Graham, is bringing red-hot Atlanta trio Migos along for the 41-date trek, hence the tour's name.
Dubbed Aubrey and the Three Amigos, the tour will start in Salt Lake City on July 26.
The tour also includes an array of Canadian dates, with the Toronto-born star playing the Air Canada Centre in his hometown on August 10 and 11.
While Los Angeles gets four shows, San Diego is not listed among the California stops.
He announced the news in a post on Twitter, billing the line-up as "a hand-picked dream team" and revealing that pre-sale begins tomorrow and all tickets go on sale on Friday.
Drake's fifth studio album Scorpion will be released in June, featuring a couple tracks that have already blown up including "God's Plan" and "Nice For What".