Trailing 2-1 to an Inter Milan side reduced to 10 men after 15 minutes, the footballing gods smiled on Juve when midfielder Miralem Pjanic, already booked, escaped a second caution for a flying bodycheck.
The UEFA Champions League provided disappointment for MLS All-Star opponent Juventus, but they will play at Mercedes-Benz Stadium having won two trophies this season.
The Frenchman's combination of expert tackling, commitment, boundless energy and tactical awareness transformed the team as they won 14 and drew two of their next 16 league games, conceding one goal in the process.
It adds to Wednesday's Coppa Italia success, meaning coach Massimiliano Allegri has won the Italian double in each of his four seasons in charge. You reach the final objective with one small step at a time.
Updates with Juventus winning title.
Napoli's title hopes were ended, despite claiming a 2-0 win over Sampdoria on Sunday evening. "It's hard to see these four years being repeated", Allegri said.
Juventus goalkeeper Gianluigi Buffon celebrates
Di Francesco says the team's development hinges on competing at the highest possible level.
Dybala threatened early and broke through early in the second half after an Alex Sandro cross but the goal was disallowed because the Argentina striker was offside.
Polish forward Arkadiusz Milik struck from distance with 18 minutes remaining, with Raul Albiol heading in a second after 80 minutes. This despite suffering a late defeat to the Partenopei in their encounter in the league a few weeks back, a loss that put them in danger of losing their title since they had tougher encounters in their schedule compared to their rivals.
Despite the impressive result, Crotone slipped into the relegation zone, below Spal on their head-to-head record.
Lazio missed a chance to clinch the fourth and final Italian place in next season's Champions League group stage when they were held to a 2-2 draw at relegation-threatened Crotone, handing a lifeline to Inter Milan who lost 2-1 at home to Sassuolo on Saturday. It visits Napoli in its final match.