Already the UFC's light heavyweight champion, Cormier becomes just the second fighter ever to hold titles in two weight classes simultaneously.
Cormier elected to drop to light heavyweight only because his friend Cain Velasquez held the UFC heavyweight belt at the time.
Speaking to the press after the event, UFC president Dana White wouldn't confirm the date or the venue, but he did confirm that Lesnar would indeed be Cormier's first UFC heavyweight title defence, saying: "We're definitely going to make that fight".
Only Conor McGregor has achieved the same feat, and Cormier's victory potentially marks the 39-year-old as the greatest UFC fighter of all time.
"The heavyweights don't move like us", Cormier said.
"It's another fight for me", he said. "I never knew what I could become, but tonight I got the answer".
The super fight between Daniel Cormier and Stipe Miocic more than lived up to the hype. "I'm coming you for, motherf*cker!" During his post-fight interview, he grabbed the microphone and called out Brock Lesnar. But when they stepped on the scales Friday morning, Cormier (246 pounds) actually outweighed Miocic (242 1/2). MMA Fighting's Dave Meltzer reported the deal allowed Lesnar to have at least one more fight in the UFC. "But everybody's strong. Push me now, you go to sleep later".
Saturday's fight was exciting from the start. "I think a lot of it depends on how he argues this case here and what USADA comes out and says about that test". Meanwhile, WWE.com ran a story about the Lesnar and Cormier confrontation and playing up the question of Lesnar's contract status with WWE.
The United States Anti-Doping Agency suspended Lesnar for one year in January 2017 because of multiple failed drug tests around UFC 200 on July 9, 2016. "I don't know where they are in the process but he is going to pop up on the board here soon".
The night's heavyweight co-main event between contender Derrick Lewis and former title challenger Francis Ngannou was expected to deliver an exciting clash, and possibly an early knockout finish. Paul Heyman has also commented... For the fourth consecutive year, the weekend's pay-per-view card lost a major fight when featherweight champion Max Holloway was ruled out of his title defence with Brian Ortega due to symptoms of an apparent concussion.