Mourinho did confirm that Alexis Sanchez, who was a highlight for United over pre-season, is fit and firing though.
Sergio Romero, Antonio Valencia, Diego Dalot, Marcos Rojo and Nemanja Matic were all unavailable for Manchester United in their most recent match due to injury - all of which are expected to remain out of action. Mourinho has suggested it may be necessary to use some of them on opening weekend.
Mourinho is desperate a new centre-back ahead of tomorrow's deadline and may revisit a move for England World Cup star Harry Maguire.
"I will have to focus on the players I have in relation to the first three matches, because after Spurs there is an global break and I have a couple of weeks to recover people and prepare them better".
Asked if his tactics that were often criticised for being too negative last season are going to change, he said: 'The target is Leicester match.
Jose Mourinho has taken aim at Liverpool and Tottenham on the eve of the new season, saying they "win nothing" but are painted as "serial winners" while his Manchester United get no credit.
Speaking to MUFC TV about the chances of World Cup players featuring in the season opener: "Rashford will be in a better situation than today".
"The manager is obviously not happy about the signings he hasn't been able to make and not having certain players available on their pre-season tour, which isn't nice to hear if you are a young kid trying to make your mark on the fringes of the squad". Let us know in the comments section.
"It is hard for me to understand, to feel, to believe we finish second - which I keep saying". "After Riyad it was important to keep our players and add some good players to strengthen the team".
"I would go for Alderweireld, all day long because he is suited to the way United play".