McTominay returns to the side as does Antony Martial & Ashley Young.
The former Juve man also worked wonders with Chelsea's defence transforming a once erratic David Luiz into one of the league's best defenders, the kind of tutelage a number of Manchester United's defenders could certainly do with.
Benitez is again without the injured Paul Dummett. One England global who recently signed a new deal at a Premier League club has a buy-out figure of £40 million for all of the clubs in the top flight, with the exceptions of United and City, who must pay £50 million to get him.
Rashford was eventually replaced by Sanchez in the 67th minute and as he left the pitch Mourinho made his feelings clear by turning away from the England forward as he made his way towards the dugout.
The controversial manager has come under fire after a poor run of form, and a report from the Daily Mirror suggested that the Portuguese manager's fate had already been sealed. "I have no doubts about that", he said. Kenedy has completed 11 take-ons in the Premier League this season, more than twice the total managed by any teammate. It promises to be a fascinating encounter as Man United take on Newcastle, with Jose Mourinho's future firmly on the line.
Manchester United are having a bad time in the Premier League this season.
Glazers are known to support managers at the club until things go completely out of hand.
Mourinho sat motionless in a short media conference on Friday when then asked if he could assure fans he was doing everything he could to try to turn things around.
"[The Newcastle game] is huge", said Neville.
Bar Cardiff or Huddersfield, United could not find an opponent lower on confidence right now than Newcastle, who have scored just twice on the road in all competitions this season and have only two away wins in all competitions in 2018.
"And I'm furious that we're stood here thinking that there's a report that's broken out. journalists don't break stories of this nature unless they're absolutely certain".