Speaking after the match Pakistan captain Sarfraz Ahmed praised the all-around performance of the team and said, "Our bowling attack is good, so we try to put some runs on the board and back ourselves to defend".
Chasing 148 for a win, Australia lost their first wicket in the third over.
For the visitors, pacer Nathan Coulter-Nile finished the innings as the most successful bowler with three wickets to his name.
Australia were clinical in the chase and the outcome of the game was never really in doubt.
"We certainly had a view as a team that we thought his bat was clearly grounded behind the line", Australia batsman Glenn Maxwell told reporters.
With Labuschagne at the non-striker's end, Mitchell Starc's drive saw Yasir Shah get a finger to the ball, and it went onto the stumps at the bowler's end.
"Maybe the third umpire pressed the wrong button". Despite being dropped twice, Glenn Maxwell scored a half-century but got out during the very last over.
Batting first, Pakistan got off to a sedate start with Babar Azam and Fakhar Zaman scoring 29 runs for the opening stand before the latter was dismissed by Coulter-Nile on the last ball of the fourth over.
Azam hit three boundaries in his 44-ball knock while Hafeez was in a more punishing mood, smashing two sixes and three boundaries off 34 deliveries.
Left-arm spinner Wasim, playing his first match for Pakistan since October past year, bowled both Australian openers, Aaron Finch (nought) and D'Arcy Short (four), in the first over of their innings. The series comprised of two tests and three T20Is.
Ranked No.1 in the world, Pakistan have now remarkably won 10 straight T20 series with Sarfraz enjoying a flawless run since replacing Shahid Afridi as skipper in 2016. Only Babar Azam, Mohammad Hafeez, and paceman Hasan Ali made respectable scores that lifted the team.
Australia - bundled out for 89 en route to a crushing 66-run defeat in Wednesday's opener in Abu Dhabi, a batting performance described by captain Aaron Finch as "like a auto crash" - made 136-8 in Dubai, Glenn Maxwell top-scoring with 52, in their pursuit of 148.
All-rounder Faheem Ashraf has enjoyed much success in global cricket with his disciplined brand of right-arm seam bowling, and he took two top-order wickets in the first game.