Mother Monster's periwinkle Valentino gown evoked images of Garland's final scene in the 1954 version of "A Star Is Born", but Gaga insists that the resemblance was unintentional.
It's not even her first Golden Globe, either. "Right now this moment is real. And now so will everyone else".
Sandra Oh accepting the award for best actress in a drama series for her role in Killing Eve.
"I discovered something working on this film, and it's something called alchemy, that you are essentially creating a character but you are really becoming the character", Gaga said about her first role as a lead movie actress.
"Bradley Cooper - you are hot!", said Oh, calling out the A Star is Born actor and director.
Vice, a scathing political comedy about the rise to power of former US Vice President Dick Cheney, went into Sunday's ceremony with a leading six nominations.
"There can be a hundred people in the room and 99 don't believe in you, but just one does, and it can change your life", Gaga has said, in various iterations with different phrasing, often gesturing to Cooper lovingly to indicate that he was her one-in-one-hundred.
Anthony Rossomando, from left, Andrew Wyatt, and Mark Ronson, right, kiss Lady Gaga, second right, after winning the award for best original song.