Air Canada said, in an emailed statement, that it was cancelling some of its 33 flights a week to China from Canada in response to the "coronavirus situation", but did not provide detailed information on which flights were being cancelled, or how many out of Vancouver were affected.
The coronavirus that originated in the city of Wuhan has killed 106 people in China and spread across the world, rattling financial markets.
Japan's Honda Motor Co Ltd said it recommended employees avoid travel to China, while Nissan Motor Co Ltd said it plans to evacuate its Japanese staff and their families in Wuhan via a government-chartered flight.
The White House is not ruling out suspending flights between the US and China because of the coronavirus outbreak, three sources confirmed to ABC News.
The flight announcements came hours after some countries began airlifts of their nationals trapped in Wuhan, the quarantined central Chinese city of 11 million people at the epicentre of the health emergency. Another source said that during a conference call on Tuesday the White House did not take the possibility of suspending flights off the table.
Hong Kong-based airline Cathay Pacific said Tuesday it has reduced its overall seat capacity on Chinese routes by half, through to the end of March.
A U.S. charter flight left Wuhan on Wednesday with about 200 Americans on board, including consulate staff.
Meanwhile, some Republican lawmakers are growing increasingly concerned with China's handling of the illness, which has killed 132 people, while 5,974 cases are under medical care.
Like other respiratory infections, it is spread by droplets from coughs and sneezes, with an incubation time between one and 14 days.
Korean Air, South Korea's biggest airline, said it is also considering grounding some of its flights to mainland China as passenger demand drops. It was the first trading session since last Thursday, with markets closed for Lunar New Year.
This horrific milestone testifies to the unnerving speed - mostly through person-to-person contact - at which 2019-nCoV is spreading on the mainland.
The World Health Organization said Tuesday it would send urgently dispatch worldwide experts to China "to guide global response efforts".
India is yet to report any positive case of coronavirus, according to the Health Ministry.
The crisis is also affecting many other global businesses: Starbucks said it would shut more than 2,000 stores in China.In its first quarter financial results Tuesday, Starbucks told investors it was closing half its 4,292 stores in China.