"While conducting maritime security operations in the US Central Command area of operations, [the USS Normandy] boarded a dhow (a traditional sailing vessel) in accordance with global law and discovered a large cache of weapons", said the US Central Command (CENTCOM) in a statement released on Thursday.
"Other weapon components seized were of Iranian design and manufacture and included three Iranian surface-to-air missiles", it said.
US sailors also confiscated three surface-to-air missiles, drone components and thermal scopes.
The weapons were "identical" to those seized in a similar operation last November by the USS Forrest Sherman.
In recent years, US warships have intercepted and seized Iranian arms likely bound for Houthi fighters in Yemen.
"The action by the Normandy in seizing the arms cache was the first publicly announced haul haul for the U.S. Navy since a January 4 drone strike at Baghdad's International Airport that killed Iranian Quds Force leader Qasem Soleimani", Military.comobserved.
Tehran is prohibited by a UN resolution from supplying, selling or transferring weapons outside Iran unless approved by the United Nations Security Council; a separate resolution on Yemen bans the supply of weapons to the Iranian-backed Houthi rebels, who are fighting the Saudi-backed Yemeni government.
"Everything points to these weapons being made in Iran".
"Everything points to these weapons being made in Iran", CENTCOM spokesman Commander Zachary Harrell told VOA.
The military said that the weapons seized on Sunday were "identical" to those seized by another USA warship in November.
The Houthi rebels in Yemen have maintained close ties to Iran, which has provided them with weapons, training and financial support.
Officials said there was no evidence to link any of the crew members to any militant groups.
The weapons seized Sunday are now in US custody awaiting final disposition.
They are now being examined by global weapons inspectors.