There have been no other young death cases reported in the United Kingdom so far, although there have been numerous reports and social media posts from young people who have caught the deadly virus.
Even Chloe's aunt, Emily Mistry wrote in a now unavailable post on Facebook that her niece "passed away of COVID-19".
Chloe Middleton from High Wycombe, Buckinghamshire died last week after contracting COVID-19 and according to her family, she had no underlying conditions.
"My handsome, kind hearted 21-year-old niece (Chloe) has passed away from COVID-19", Ms Mistry wrote.
"The reality of this virus is only just unfolding before our very eyes". She had no underlying health issue'.
Chloe Middleton's devastated family shared the news of her death in the hope it will act as a wake-up call to those ignoring social distancing rules.
"She had no underlying health conditions".
She said the family had been "shattered beyond belief" by the death.
She is one of many coronavirus patients sharing their stories online in a bid to stop the public being reckless.
"Please, please adhere to government guidelines".
An 18-year-old man who died in hospital at the weekend after testing positive was being treated for "significant underlying health issues".
World Health Organisation Director-General Tedros Adhanom Ghebreyesus said: "Although older people are hardest hit, younger people are not spared".
"Even if you don't get sick the choices you make about where you go could be the difference between life and death for someone else".
"I am telling you now, if you are going to meet your friends for a stupid beer or for a walk because the weather is nice, you are going to take this home and you are going to kill someone", she warned.