Some have gone down well, others less so. While he did have a serious message for Canadians to 'stay at home, practice social distancing, wash your hands, ' he also jokingly questioned if he was the right person to spread the public health message.
"Look, stay at home".
And help him they did, with Reynolds and Buble posting their own videos and each asking fellow Canadians - including Seth Rogan, Stephen Page of the Barenaked Ladies, Shawn Mendes, Jason Priestly, YouTuber Lilly Singh and others - to do the same. Watch this doctor's powerful speech. Ryan joked, "I think we all know that it's the celebrities we count on most" during hard times. "They're the ones that are going to get us through this - right after healthcare workers, of course, first responders, people who work in essential services", he said in his signature self-deprecating humour, adding mannequins, childhood imaginary friends and "400 other types of people" who were more important than celebrities.
Like, let's say Seth Rogen were to ever meet Kim Kardashian at a part - I wonder what goes through his mind. "We are going to get through this thing together", he said.
Rather than taking to his Instagram to sing a song like Hugh Jackman or Gal Gadot, Ryan Reynolds recently uploaded a post to his Instagram poking fun at celebrity self-importance.
As of 6pm EDT yesterday, there were 1,646 confirmed cases of coronavirus in Canada, with 24 people having died from the disease. Over 14,600 people have died.