Shops will roll out in coming months to some 160 million businesses that already use the social network.
Almost a million businesses in the United Kingdom and around the world can now set up a single online store to sell products, with no fee, on Facebook and Instagram.
Zuckerberg said that Facebook Shops will eventually include augmented reality, allowing customers to try items on from home.
"It's one simple and consistent experience across this family of apps, which means it is easier for people", Zuckerberg said in a live stream on Facebook.
"Our mission is about giving individuals the power to bring people closer together".
"Because even when this period and the lockdowns pass ... we're going to continue living more of our lives, and doing business, online".
Users can discover Facebook Shops either on the brands' Facebook or Instagram page, or through Stories and ads on both platforms. Sure, over time, there have been moves to satisfy the needs of businesses that want to reach customers and sell their wares on Facebook and Instagram, but efforts haven't been holistic enough to be called "well-rounded".
Facebook will also introduce loyalty programmes for the Facebook account.
"From there, you can browse the full collection, save products you're interested in and place an order - either on the business' website or without leaving the app if the business has enabled checkout in the USA", informed the company. Small businesses will be able to find users on Facebook pages and Instagram profiles, and their ads will also appear on Facebook or Instagram stores. But, when you use Facebook to checkout, you will reportedly be charged a fee.
Stores on Facebook allows any business, from a small business to a global brand, sell your products through Facebook.
"Facebook Shops has the potential of offering small to mid size businesses a seamless journey from conversation to conversion", added Ms Shaikh.
Facebook says it is working on ways to allow merchants to feature and link products from Facebook Shops in live videos.
And while Facebook Shops starts rolling out today, Instagram Shops will make its debut this summer in the US. In the future, customers will be able to view a business' shop and make purchases within chats in WhatsApp, Messenger, or Instagram Direct.
In the United States, customers will be able to check out directly within Facebook - though this feature has yet to make it to Australia and New Zealand. Users can then hop in, browse the product catalog, and buy the goods they like without ever leaving any of the social apps.