"We're going to be the most forward-leaning company on remote work at our scale", Zuckerberg told The Verge.
The social network's chief set out his vision to employees on Thursday, prompted by the current coronavirus crisis which has forced companies across the globe to embrace remote working in recent months.
"How do we encourage creativity when we are seeing each other less, what's the best way to make sure everyone has equal opportunities ... hiring remotely should help, but if remote work ends up being harder, how do we prevent that from affecting people". The company will begin by focusing on hiring for advanced engineering positions, Zuckerberg said.
At Facebook, more than 95% of full-time employees have been working from home during the COVID-19 pandemic. Both Twitter and now Shopify have also made a decision to let some employees work remotely on a permanent-basis. "But we're going to do this in a way that is measured and thoughtful and responsible, and in phases over time".
"We'll adjust salary to your location at that point", he said, noting it will be necessary to take taxes into account. "So, that just means that we're going to have a lot of people who want to go back to the offices but aren't going to be able to".
"A 25-year-old maybe would rather be in San Francisco, while someone looking to raise a family might prefer to move outside the city", he said.
"Since so much of what we build is around helping people feel connected no matter where they are - like our messaging apps, video chat and eventually virtual and augmented reality - living our values will help us accelerate the development of these technologies", noted Mr Zuckerberg. It'll also involve addressing certain challenges, like ensuring remote workers don't lose out on career advancement.
Last week, social media giant Twitter announced it will allow its entire workforce to work from home permanently.
Shopify boss Lütke tweeted: "As of today, Shopify is digital by default. Office centricity is over". The company has been thriving as retailers move online due to coronavirus restrictions.
Prior to the pandemic, the focus of big USA tech companies had been to have all employees working together at huge headquarters, some including Facebook, offering employees bonuses to live nearby.
"Earlier today, we announced the extension of our work-from-home arrangement for all Spotify employees globally".
"Our employees' health and safety is our top priority". Facebook also uses its own apps to track employee locations, according to CNBC, once using the data to find interns who failed to show up for work.