Harvard study explains how COVID-19 causes loss of smell

Study detects heart damage in majority of recovered COVID-19 patients

German coronavirus studies identify heart issues in COVID-19 patients

For the study, around 100 patients who recently recovered from COVID-19 were identified from the University Hospital Frankfurt COVID-19 Registry between April and June 2020.

As Covid-19 progresses, one thing is certain - science moves quickly and new discoveries about the virus are made nearly daily.

COVID-19 patients are 27 times more likely to have smell loss than those without the disease, but are only around 2.2 to 2.6 times more likely to have fever, cough or respiratory difficulty, the experts said.

Some COVID-19 sufferers, however, experience anosmia with no nasal obstruction.

Image: A microscopic image shows SARS-CoV-2 from a patient in the US.

How will the research impact the future of Covid-19 and school regulations?

In a second study involving autopsies from 39 COVID-19 cases, researchers found a presence of viral infection within the myocardium or the middle, muscular layer of the heart, in 24 patients. This suggests a degree of cardiovascular damage seems to result from the disease regardless of the severity of the acute illness or the presence of any pre-existing conditions. They were "mostly healthy" before they got sick, the researchers said.

Viral loads in older children with COVID-19 are similar to levels in adults.

The findings also offer intriguing clues into COVID-19-associated neurological issues.

The patients' median age was 85 years, and pneumonia was listed as the cause of death for 90 percent of them. In addition, 76 of those patients had a biomarker usually found in heart attack patients, and 60 had heart inflammation. Sixteen of the subjects were found to have clinically significant levels of viral load in their heart tissue at the time of death.

The study also "adds to mounting evidence discrediting conspiracy theories that suggest SARS-CoV-2 was bio-engineered or escaped from a laboratory", The Telegraph reported citing the authors. "We don't know what the long-term effects of that may be, but it could be that we will have a population of people who survive COVID-19 only to go on and have chronic cardiac problems".

"But we need more data and a better understanding of the underlying mechanisms to confirm this conclusion".

For the study, published in JAMA Pediatrics, the team collected nasopharyngeal swabs from inpatient, outpatient, emergency department, and drivethrough t children at a pediatric tertiary medical center in Chicago. "... if this high rate of risk is confirmed, the pathologic basis for progressive left ventricular dysfunction is validated, and especially if longitudinal assessment reveals new-onset heart failure in the recovery phase of COVID-19, then the crisis of COVID-19 will not abate but will instead shift to a new de novo incidence of heart failure and other chronic cardiovascular complications".

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