Although it's unknown where Cain contracted the virus due to his heavy travel schedule, a number of Trump's campaign staffers and Secret Service agents self-isolated after the Tulsa rally due to fear of exposure.
"Herman had an incredible career and was adored by everyone that ever met him, especially me", the president wrote.
In the post, Calabrese detailed the final weeks of Cain's life, reporting that Cain was hospitalized after testing positive for the virus several weeks ago after he was having difficulty breathing.
"He was a very special man, an American Patriot, and a great friend", continued Trump.
Every single Trump tweet is met with strong opinionated responses, both supporting and attacking him, and the trend continued today as numerous replies to Trump's tweet followed the tone of ones earlier in the day blaming Trump and the Tulsa rally for Cain's death.
In 2012 he was briefly the front-runner for the Republican presidential nomination, but later withdrew from that year's race after three women accused him of sexual harassment. "We wish his family well and we wish that he rest in peace and I wish this president have no peace until he thinks about what he's exposing people to".
"That's when I prayed and prayed and prayed", he told an audience of young Republicans in Atlanta.
But while social media was buzzing, the president was holding a roundtable at the White House on the issue of donating plasma. He went on to obtain a bachelor's degree in mathematics and a master's in computer science.
While it was a good job, Mr Cain said his ambitions were in the corporate world.
Cain served as the former CEO of Godfather's Pizza and entered politics in 1996 where he served as senior advisor for Bob Dole's presidential campaign. He is the one who worked first for Coca-Cola, became a vice president with Pillsbury, then was appointed to run its struggling Burger King unit in the Philadelphia area.
Mr Cain said he returned the franchise to profitability.
Cain is survived by his wife, Gloria Etchison, who he married in 1968, and two children.