Officials say the state will discard the color-coded "Blueprint to a Safer Economy" the four-tier, color-coded system that guided economic reopening through a series of restrictions and capacity limits.
California, the governor noted, has already administered 20 million doses, more "than all but five nations in the world" and anticipates 30 million people across the state will have received at least one dose by the end of April.
Face mask mandates will still be in place.
Regarding the reopening of schools, Newsom said that counties could still have their own restrictions past June 15, but he hoped all schools would reopen.
Now, the new plan says businesses can open with "common-sense risk reduction measures" such as wearing masks and encouraging vaccinations.
A statewide mask mandate will stay in effect, Newsom said, and he cautioned that California will reopen more widely in mid-June only if vaccine supply is sufficient and hospitalization rates stay stable and low.
Schools will be allowed to conduct full-time, in-person instruction if following public health guidelines, and large-scale indoor events will be capped at 5,000 people through October 1 unless testing or vaccination status is verified for all attendees.
"We can now begin planning for our lives post-pandemic", Newsom said. "We will be getting rid of the blueprint as you know it today". All counties across the state will make the move to reopen simultaneously.
Gavin Newsom said in a tweet that California has the lowest positivity rate in the country. "We are seeing a bright light at the end of the tunnel".
"The population of 16-plus, among that population are those that defied all guidance and went to places like South Beach in Miami in crowds", she said.
Gov. Gavin Newsom took the podium to announce the change to the public, saying that, provided there is no fresh surge of COVID-related infection and provided that current vaccine supply estimates for the coming two months prove out in the real world, it should be OK for the vast majority of businesses and organizations statewide to reopen at full capacity more than two weeks before the Fourth of July.
California is now operating under a patchwork of capacity restrictions that pivot on local infection and hospitalization rates.
Meanwhile, in the Bay Area, eight out of nine counties are now in the "Orange" tier - Sonoma, Napa, and Contra Costa counties were promoted on Tuesday, and now only Solano County remains in the "Red", along with neighboring counties like Sacramento and San Joaquin. Newsom said there is an expectation that students will return to in-person learning, but stopped short of calling it a requirement.