A white SUV pulled up to the location and three people got out with assault weapons and handguns and started firing into the crowd that was gathered for a concert at the venue, USA news channel CNN reported.
"The result is 20 to 25 victims with gunshot injury wounds, and two deceased on the scene".
Authorities believe the shooting was targeted.
"These are cold-blooded murderers that shot indiscriminately into a crowd, and we will seek justice", he said.
Angelica Green, of Miramar, told reporters her son and nephew, both 24, were arriving at the event when they became among those shot and wounded.
At least one of the wounded is in a critical condition, police said.
Officers say three people stepped out of a white SUV and began shooting into the crowd.
The police are asking for the public's help in bringing the shooters to justice.
It is the second shooting to come over Memorial Day weekend in Miami.
In March past year, the number of weekly federal background checks on gun buyers surpassed one million for the first time, the New York Times reported.
Mass shootings have occurred in recent months at a FedEx facility in Indianapolis, an office building in California, a grocery store in Colorado and at several spas in Atlanta.
The United States counted the deaths of more than 43,000 people with firearms previous year, including suicides, according to the "Archives of Weapon Violence".
"All of this of course coming at the back of a huge spike in gun violence in this country", he added.
President Joe Biden last month branded USA gun violence an "epidemic" and an "international embarrassment".
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